This article argues against the present government educational monopoly and explains why taxpayers should not be forced to subsidize what is, in effect, anestablishment of a "religion" of secularism. It argues that parents in justice have a right to have the wherewithal to have genuine choice in the education of their children.

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

This book explores how and when biology emerged as a science in Germany. Beginning with the debate about organism between Georg Ernst Stahl and Gottfried Leibniz at the start of the eighteenth century, John Zammito traces the development of a new research program, culminating in 1800, in the formulation of developmental morphology. He shows how over the course of the century, naturalists undertook to transform some domains of natural history into a distinct branch of natural philosophy, which attempted not (...) only to describe but to explain the natural world and became, ultimately, the science of biology. (shrink)

Exploring the relationship between morality and professional ideals, Kultgen examines the structure and organization of occupations and the ideals and ideology associated with professions. He argues that professionalization of occupations can both harm and benefit society, and that by converting occupations into organized special interest groups, the professions serve some sectors of society at the expense of others. On the other hand, he highlights the positive points of the professional ideal and explores ways in which it can be used to (...) advance the physical and moral welfare of society. Kultgen also shows how it is the practices within the professions that determine whether rules and ideals are used as masks for self-interest or for genuinely moral purposes. ISBN 0-8122-8094-6: $14.95. (shrink)

There is an unspoken distinction in ethical criteria in bioethics. On the one hand, there are criteria that can be used with discretion and judgment by an individual or small group of people like a...

While functioning quite well for many years, the bioethics profession is in crisis. John H. Evans closely examines the history of the bioethics profession, and based on the sociological reasons the profession evolved as it did, proposes a radical solution to the crisis.

Kant’s philosophy of science takes on sharp contour in terms of his interaction with the practicing life scientists of his day, particularly Johann Blumenbach and the latter’s student, Christoph Girtanner, who in 1796 attempted to synthesize the ideas of Kant and Blumenbach. Indeed, Kant’s engagement with the life sciences played a far more substantial role in his transcendental philosophy than has been recognized hitherto. The theory of epigenesis, especially in light of Kant’s famous analogy in the first Critique, posed crucial (...) questions regarding the ‘looseness of fit’ between the constitutive and the regulative in Kant’s theory of empirical law. A detailed examination of Kant’s struggle with epigenesis between 1784 and 1790 demonstrates his grave reservations about its hylozoist implications, leading to his even stronger insistence on the discrimination of constitutive from regulative uses of reason. The continuing relevance of these issues for Kant’s philosophy of science is clear from the work of Buchdahl and its contemporary reception. (shrink)

In response to Flamm and Kodish, I argue that our misunderstanding or disagreement is primarily the result of different definitions of power. I also disagree with them and claim that they are indeed using the public’s ethics. Finally, I argue that there is no reason to think that bioethicists cannot have the same sort of influence in the boardroom that they have in the clinic.

This chapter discusses the various meanings of the two critical ideas in this book and compares them. These critical ideas are “religion” and “public bioethics”. The chapter focuses most of all not on the different religious roles, but on what we think “public bioethics” is or should be.

History-based trade books, such as biographies, narrative non-fiction, and expository texts, are essential secondary sources in social studies classrooms. Research, though, indicates a preponderance of misrepresentations in trade books’ depictions of historical eras and figures. We examined trade books’ historical representation of John Fitzgerald Kennedy, an iconic American president. The data sample featured biographies targeting various grade-ranges and published in different eras. Including books targeting early grade, middle grade, and high school students enabled comparisons of historical representation within and (...) between different grade-ranges. Incorporating texts published in different eras allowed for consideration of how Kennedy's historical representation changed over time. Mixed methods content analysis—reliant on both open and axial-coding—yielded important findings about how children's and young adult authors depicted Kennedy's family history, particularly during World War II, privileged social position, Catholicism, wife, health, tensions during his presidency, and his assassination and subsequent conspiracy theories. Trade books’ representations appeared to be shaped more by date-of-publication than intended age of the reader. Identified historical misrepresentations included presentism, omission, exceptionalism, and heroification. Significance for teachers and researchers is articulated and practical classroom suggestions are provided. (shrink)

The two theories that revolutionized physics in the twentieth century, relativity and quantum mechanics, are full of predictions that defy common sense. Recently, we used three such paradoxical ideas to prove “The Free Will Theorem” (strengthened here), which is the culmination of a series of theorems about quantum mechanics that began in the 1960s. It asserts, roughly, that if indeed we humans have free will, then elementary particles already have their own small share of this valuable commodity. More precisely, if (...) the experimenter can freely choose the directions in which to orient his apparatus in a certain measurement, then the particle’s response (to be pedantic—the universe’s response near the particle) is not determined by the entire previous history of the universe. Our argument combines the well-known consequence of relativity theory, that the time order of space-like separated events is not absolute, with the EPR paradox discovered by Einstein, Podolsky, and Rosen in 1935, and the Kochen-Specker Paradox of 1967 (See [2].) We follow Bohm in using a spin version of EPR and Peres in using his set of 33 directions, rather than the original configuration used by Kochen and Specker. More contentiously, the argument also involves the notion of free will, but we postpone further discussion of this to the last section of the article. Note that our proof does not mention “probabilities” or the “states” that determine them, which is.. (shrink)

Volume 19, Issue 7, July 2019, Page 32-34.

In this book, John H. Smith investigates the influences of classical and humanistic rhetoric on Hegel's theory and practice of philosophical representation. Smith focuses on Hegel's concept of Bildung (roughly, education, development, or formation) which occupies a central position in his philosophy.

This book is a study of comparative philosophy and theology. The themes are the critical issues arising from the modern interpretation of Confucian doctrine as they confront the Christian beliefs of the nineteenth and twentieth centuries.

The basic relationship between people should be care, and the caring life is the highest which humans can live. Unfortunately, care that is not thoughtful slides into illegitimate intrusion on autonomy. Autonomy is a basic good, and we should not abridge it without good reason. On the other hand, it is not the only good. We must sometimes intervene in the lives of others to protect them from grave harms or provide them with important benefits. The reflective person, therefore, needs (...) guidelines for caring. Some contemporary moralists condemn paternalism categorically. This work examines weaknesses in their arguments and proposes new guidelines for paternalism, which it calls "parentalism" to avoid the patriarchal connotations of the old term. Its antiparentalism is more moderate than standard antipaternalism based on an exaggerated respect for autonomy. The work explores implications for both the personal sphere of interactions between individuals, such as friends and family members, and the public sphere of institutions, legislation, and the professional practices. (shrink)

Sawai et al. (2022) provide a good summary of the bioethical debate about brain organoids with an eye toward future directions. Like many contemporary texts in bioethics, they call for engagement w...

In lieu of an abstract, here is a brief excerpt of the content:Machiavelli’s Moses and Renaissance PoliticsJohn H. GeerkenWithin the almost Dantesque array of humanity that populates the pages of Machiavelli’s canon, Moses occupies a special place. He first appears in chapter six of The Prince concerning those who acquire new princedoms by dint of their own virtù and military self-sufficiency. He last appears in the Discourses as one who was forced to kill a host of envious opponents. There is (...) some irony in these representations: in The Prince, with its tyrannical overtones, Moses appears as God’s friend; but in the Discourses, with its republican associations, Moses is an executioner. Machiavelli captures some of the ambiguity that attends on Moses when he declares that “Moses should not be discussed, since he was a mere executor of things laid down for him by God, nevertheless he ought to be exalted, if only for the grace that made him worthy to speak with God.” 1 Are we to exalt Moses, but not discuss him? Then, too, why bother with either God or Moses? Why complicate the search for the effectual truth of things by invoking metaphysical elements or inimitable biblical figures? How are we to understand these references? Are these ironic as sometimes asserted?But what are the heuristic possibilities in a non-ironic approach? If Moses had so great a teacher, what was his curriculum? Since no other figure in the Machiavellian census is so associated with slavery, was Moses a vehicle for making an assertion about slavery and liberation, or about politics and religion, or about the morality of politics? Then, too, how did Machiavelli’s Moses compare to the Moses who was so prominent in Renaissance iconology? These are the questions which this study addresses.I. Of the several references to Moses, the most telling is the last one in the Discourses. Machiavelli writes: “He who reads the Bible intelligently [sensata-mente] [End Page 579] sees that if Moses was to put his laws and regulations into effect, he was forced to kill countless men who, moved by nothing else than envy, were opposed to his plans.” 2A great deal is compressed into this passage: the confrontation of Moses’ virtù with the necessity imposed by his opposition, the need to use violent means to achieve lawful ends, and the implied sanction of sacred Scripture. But the Bible, Machiavelli asserts pointedly, must be read intelligently—presumably not in a devotional, liturgical, or exegetical manner, but in effect politically. Machiavelli wrote that he himself read in order to learn the reasons for human actions. 3 Indeed, one of his reasons for writing history was to convey his conviction that “[i]f any reading is useful to citizens who govern republics, it is that which shows the causes of the hatreds and factional struggles within the city, in order that such citizens having grown wise through the sufferings of others, can keep themselves united.” 4In a word reading can be political. References to biblical figures in his works indicate that for Machiavelli the Bible was not exempt from a political reading; it, too, could yield the reasons for human actions and the causes of hatred and factionalism. 5 We can assume, therefore, that he read the Book of Exodus with these concerns in mind even as he invited his own readers to read the Bible. What, therefore, can the Book of Exodus show us?II. The Book of Exodus records at least forty-three conversations between God and Moses, thirty-three of which were initiated by God in order to instruct, command, announce, predict, threaten, remind, warn, and legislate. It records God’s determination to rescue his convenanted people despite pharaoh’s sustained resistance. 6 It records as well the instructional conversations dealing with the plagues, the sacrifices, the Passover, the plundering of Egypt, the escape routes and the encampments. 7 And of course there is the account of the crossing of the Red Sea which no Egyptian pursuer survived. 8Noteworthy, too, is the fact that, for his part, Moses initiated ten conversations with God, declaring his personal doubts and inadequacies, offering his excuses, complaining about the hardships of his mission, reporting on the grumbling... (shrink)

This commentary supports Barzykowski and Moulin's model, but departs from it on the question of functionality, where IAMs and déjà vu fractionate. The authors seem to say that IAMs are functional, while déjà vu is not. As there is no hard evidence supporting the idea that IAMs are functional, I argue that both phenomena should be viewed as cognitive failures.